Weight Loss: Do MIC & B12 Injections Really Work?

By Dr. Stephen Cosentino

Weight Loss: Do MIC & B12 Injections Really Work?

Methionine inositol choline (MIC) and Vitamin B12 injections are inexpensive, minimally invasive procedures that boost energy and increase metabolism of fats. They’re touted as safe, reliable weight loss treatments.

But do they work?

The short answer is yes, often. While individual results may vary, B12 and MIC injections can facilitate weight loss as part of a broader clinician-supervised program. MIC and B12 injections can lead to a weight loss of 2-4 pounds per week when combined with lifestyle changes.

And because both are essential nutrients, many patients prefer MIC/B12 treatments to riskier or more invasive pharmaceutical or surgical alternatives.

What Are MIC and B12 Injections?

MIC and B12 shots are typically administered together, as a single injection of a blended cocktail. Each component plays an important role in the solution’s body fat-burning mechanism, however. Here’s how B12, methionine, inositol, and choline combine work after injection.

Methionine

Methionine is an essential amino acid that’s found in lean meats, dairy, and nuts. It assists with the breakdown of excess body fat in the liver and can help reduce the blood triglycerides associated with elevated “bad” cholesterol readings.

Inositol

Inositol is a B-complex vitamin that helps metabolize fats. It also plays a role in regulating serotonin, an important neurotransmitter that can affect the appetite. As a serotonin regulator, inositol may also have benefits for patients’ mental health, though it’s not approved to treat specific mental health conditions.

Choline

Choline is a water soluble essential nutrient that promotes liver function. It also plays a role in transporting metabolic products, including fats, through the bloodstream. Like methionine, choline plays a role in regulating blood triglycerides and cholesterol.

B12

Vitamin B12 is an essential vitamin that complements and magnifies the effects of inositol, methionine, and choline. It increases the body’s metabolic rate and may assist in the breakdown of excessive fats, help the body increase red blood cell production, and increase energy levels.

Benefits of MIC and B12 Injections

The four active ingredients in fat burning MIC and B12 treatments have some important observed benefits for patients looking to lose weight and feel better:

Assisting in the breakdown of fat in the liver and bloodstream
Promoting controlled weight loss when combined with positive changes in diet and exercise
Improving energy levels and overall mood
Suppressing appetite and reducing cravings for food
Regulating sleep periods and sleep quality

Patients should have realistic expectations, as results can vary and may take several weeks or months to become visible. Consistent, regular use of the injections is typically required to maintain any benefits.

Are MIC and B12 Injections Safe?

MIC and B12 injections are widely regarded as effective by clinicians who use them. Years of clinical data suggest they’re also safe for most patients when used under the close supervision of a trained medical weight loss provider. It's important for patients to discuss any allergies or medical conditions with their provider before receiving MIC and B12 injections.

Typically, providers aim to achieve gradual weight loss of one to two pounds per week during the course of treatment.

MIC and B12 treatments do have some documented side effects. These are mainly mild and temporary, such as:

Redness, swelling, or soreness around the injection site
“Flushed” feeling after the injection
Temporary lightheadedness after the injection
Temporary upset stomach or nausea

These side effects usually resolve within a few hours to a few days. They’re less likely to occur or persist in patients working with trained clinicians — clinicians who may also be trained to provide other minimally invasive aesthetic and medical treatments, such as Botox and dermal filler injections.

MIC and B12 Injections as Part of a Comprehensive Weight Loss Plan

It's important to emphasize that MIC and B12 injections are not a standalone solution for significant, long-term weight loss. While they can provide a helpful boost to support fat metabolism and energy levels, these injections work best as part of a comprehensive weight loss program that also includes other key components.

A Holistic Approach to Weight Loss

For optimal results, MIC and B12 injections should be combined with the following elements as part of an overall weight management plan:

Healthy, Calorie-Controlled Diet

A nutritious, calorie-controlled diet is essential for sustainable weight loss. This should include:

Emphasis on whole, nutrient-dense foods like fruits, vegetables, lean proteins, and complex carbohydrates
Appropriate calorie intake based on individual needs and weight loss goals
Balanced macronutrient ratios (e.g. 40% carbs, 30% protein, 30% fat)
Guidance from a registered dietitian or nutritionist, if needed

Regular Physical Activity

Regular exercise is crucial for boosting metabolism, burning calories, and building muscle. An effective exercise regimen may include:

150-300 minutes per week of moderate-intensity activity, such as brisk walking, swimming, or cycling
2-3 sessions per week of strength training to maintain and build lean muscle mass
Low-impact activities like yoga or pilates to improve flexibility and balance

Behavioral Modifications

Addressing the behavioral and psychological aspects of weight loss is just as important as diet and exercise. Strategies may include:

Working with a therapist or counselor to identify and address emotional eating triggers
Developing healthy coping mechanisms for stress and anxiety
Practicing mindfulness and intuitive eating techniques
Setting realistic, achievable goals and celebrating non-scale victories

Regular Medical Supervision

Throughout the weight loss journey, it's essential to work closely with a qualified healthcare provider who can:

Monitor progress, adjust the treatment plan as needed, and provide ongoing support
Ensure the safe and appropriate use of MIC and B12 injections and other weight loss interventions
Address any underlying health conditions that may be impacting weight

By incorporating MIC and B12 injections into a comprehensive, multifaceted weight loss program, individuals can maximize their chances of achieving sustainable, long-term results.

Patients should work closely with their healthcare provider to determine if MIC and B12 injections are an appropriate addition to their weight loss regimen.